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Croyezbio

SKU:CR00021-1MG

GFP Self-Amplifying RNA (saRNA), Unmodified – 8.5 kb Reporter RNA

GFP Self-Amplifying RNA (saRNA), Unmodified – 8.5 kb Reporter RNA

Regular price $3,000.00 USD
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Package
SELF-AMPLIFYING RNA · GFP REPORTER

Evaluate saRNA Delivery & Expression With a GFP Reporter

An 8,476 nt GFP self-amplifying RNA designed as a ready-to-use reporter for saRNA delivery, transfection, formulation and expression research.

RNA LENGTH
8,476 nt
REPORTER
GFP
5' CAP
Cap 1
PACKAGE
100 µg

Why Start With a GFP Reporter saRNA?

Developing a new saRNA delivery system often requires optimization before moving to a target RNA construct. A GFP reporter provides a straightforward functional readout for comparing experimental conditions.

CR00021 provides a long self-amplifying RNA construct that can be used to evaluate delivery and expression in saRNA research workflows.

DELIVERY

Delivery Screening

Compare candidate RNA delivery conditions using GFP expression as a functional readout.

FORMULATION

LNP Development

Evaluate experimental lipid nanoparticle formulations for long-RNA delivery.

EXPRESSION

saRNA Expression

Study expression from a GFP-encoding self-amplifying RNA construct.

A Straightforward Fluorescent Readout

GFP expression provides a convenient reporter signal for comparing delivery and expression across experimental conditions using common fluorescence-based research methods.

GFP FLUORESCENCE
Ex / Em: 505 / 525 nm

A Practical saRNA Evaluation Workflow

STEP 01
Prepare Delivery System
STEP 02
Deliver GFP saRNA
STEP 03
Measure GFP Expression
STEP 04
Compare Conditions

Product Specifications

Catalog Number CR00021-1mg
Product GFP Self-Amplifying RNA / GFP saRNA (Unmodified)
RNA Length 8,476 nt
Reporter GFP
Base Composition Unmodified bases
5' Cap Cap 1
Poly(A) Tail Yes
Concentration 1.0 mg/mL
Package 100 µg
Form Liquid
Buffer 1 mM sodium citrate, pH 6.4
Storage −80°C or below; avoid repeated freeze/thaw cycles
LONG RNA QC

Working With an 8.5 kb RNA?

At 8,476 nt, CR00021 extends beyond the upper reference range of many conventional RNA markers. A higher-range ladder can provide more useful reference points when evaluating long RNA by electrophoresis.

RNA QC 01 · SIZE & INTEGRITY

12K High Range RNA Ladder

Nine ssRNA reference bands from 200 nt to 12 kb, including 9 kb and 12 kb reference bands.

View CR00005 →

Extend Your saRNA QC Workflow

Size, dsRNA impurity and process residuals represent different analytical questions in an IVT RNA workflow.

DANA BIOSCIENCE · saRNA RESEARCH

Build Your saRNA Research Workflow

Start with a GFP reporter saRNA and connect delivery, expression and complementary RNA quality-control tools in one research workflow.

Explore RNA QC Solutions →

For Research Use Only. Not for diagnostic or therapeutic use. Expression results may vary depending on cell type, delivery method, formulation and experimental conditions.

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