Dana Bioscience RNA QC Solutions

Long RNA, mRNA & saRNA Quality Control

Tools for RNA size, integrity and dsRNA impurity analysis — from conventional IVT RNA to long self-amplifying RNA constructs.

Start With the QC Question

What are you trying to measure?

Is my RNA the expected size?

Use an RNA ladder with a reference range that covers your transcript length.

Is the RNA intact?

Evaluate migration and band patterns to identify degradation or unexpected transcript products.

How much dsRNA impurity is present?

Use a J2-based dsRNA ELISA for quantitative residual dsRNA analysis.

RNA Ladder Selection Guide

Choose the reference range that matches your RNA.

General Range

6K RNA Ladder

CR00004

For conventional IVT RNA and transcripts within the standard size range.

Extended Range

9K Mid Range RNA Ladder

CR00039

For longer mRNA and RNA constructs extending beyond 6 kb.

Long RNA / saRNA

12K High Range RNA Ladder

CR00005-50UL

Nine ssRNA references covering 0.2 to 12 kb for long IVT RNA, mRNA and saRNA applications.

Ultra High Range

15K Ultra High Range RNA Ladder

CR00042-25UL

6, 9, 12 and 15 kb reference bands for very large RNA constructs.

Featured Product

12K High Range RNA Ladder

When conventional RNA markers stop short, extend your reference range to 12 kb.

Band sizes

0.2 / 0.5 / 1 / 2 / 3 / 4 / 6 / 9 / 12 kb

Format

50 µL

Application

ssRNA size reference for native agarose gel electrophoresis

Useful for

Long IVT RNA, long mRNA, saRNA and other large RNA constructs

0.2 kb → 12 kb ssRNA reference
Size Is Only Part of RNA QC

Pair RNA size analysis with dsRNA impurity measurement.

RNA Size & Integrity

High-range RNA ladders provide size references for long RNA analysis by agarose gel electrophoresis.

  • Expected transcript size
  • Long RNA migration reference
  • Visual integrity assessment

dsRNA Impurity

The J2-based dsRNA ELISA provides quantitative detection of residual double-stranded RNA in research workflows involving IVT RNA.

  • Quantitative dsRNA measurement
  • 96-well ELISA format
  • IVT mRNA and RNA purification research
Applications

Built for modern RNA research workflows.

IVT mRNA

Assess transcript size and support impurity analysis during in vitro transcription research.

Self-Amplifying RNA

Long saRNA constructs may require reference ranges beyond conventional RNA ladders.

RNA Therapeutics R&D

Build a practical research QC workflow for long RNA development, optimization and comparison studies.

Dana Bioscience RNA QC Solutions

Working with long RNA or saRNA?

Start with the 12K High Range RNA Ladder, or contact Dana Bioscience if you need help selecting the appropriate RNA QC tools for your workflow.

For Research Use Only. Product specifications and recommended experimental conditions should be confirmed in the applicable manufacturer documentation.