ZRANB1 Antibody

Size

100ul

Clone Number

Aliases

DKFZp762P2216 antibody; hTrabid antibody; Trabid antibody; TRAF-binding protein domain antibody; Ubiquitin thioesterase ZRANB1 antibody; Zinc finger Ran-binding domain-containing protein 1 antibody; ZRAN1_HUMAN antibody; ZRANB1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UGI0

Immunogen

Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500

Background

Specifically hydrolyzes \'Lys-29\'-linked and \'Lys-33\'-linked diubiquitin. Also cleaves \'Lys-63\'-linked chains, but with 40-fold less efficiency compared to \'Lys-29\'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ZRANB1

Research Areas

Epigenetics and Nuclear Signaling; Cell biology; Stem cells