ZNF423 Antibody, Biotin conjugated

Size

100ul

Clone Number

Aliases

Early B cell factor associated zinc finger protein antibody; Ebfaz antibody; hOAZ antibody; JBTS19 antibody; KIAA0760 antibody; NPHP14 antibody; Nur12 antibody; OAZ antibody; OLF 1/EBF associated zinc finger antibody; OLF1/EBF associated zinc finger protein antibody; Olf1/EBF-associated zinc finger protein antibody; Roaz antibody; Smad and Olf interacting zinc finger protein antibody; Smad- and Olf-interacting zinc finger protein antibody; Zfp104 antibody; ZFP423 antibody; zinc finger protein 423, mouse, homolog of antibody; Zinc finger protein 423 antibody; ZN423_HUMAN antibody; ZNF423 antibody; ZNF423 zinc finger protein 423 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q2M1K9

Immunogen

Peptide sequence from Human Zinc finger protein 423 protein (39-57AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ZNF423

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction