ZMYND11 Antibody

Size

100ug

Clone Number

Aliases

ZMYND11 antibody; BRAM1 antibody; BS69 antibody; Zinc finger MYND domain-containing protein 11 antibody; Adenovirus 5 E1A-binding protein antibody; Bone morphogenetic protein receptor-associated molecule 1 antibody; Protein BS69 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15326

Immunogen

Recombinant Human Zinc finger MYND domain-containing protein 11 protein (363-513AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at \\\'Lys-36\\\' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ZMYND11

Research Areas

Epigenetics and Nuclear Signaling; Cell biology; Immunology