ZFPM2 Antibody

Size

100ul

Clone Number

Aliases

FOG-2 antibody; FOG2_HUMAN antibody; Friend of GATA 2 antibody; Friend of GATA protein 2 antibody; Friend of GATA2 antibody; hFOG-2 antibody; ZFPM2 antibody; Zinc finger protein 89B antibody; Zinc finger protein M2 antibody; Zinc finger protein multitype 2 antibody; Zinc finger protein ZFPM2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8WW38

Immunogen

Recombinant Human Zinc finger protein ZFPM2 protein (982-1151AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2 (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ZFPM2

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Cardiovascular