ZFP57 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

ZFP57 antibody; C6orf40 antibody; ZNF698 antibody; Zinc finger protein 57 homolog antibody; Zfp-57 antibody; Zinc finger protein 698 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NU63

Immunogen

Recombinant Human Zinc finger protein 57 homolog protein (183-295AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Binds to a 5\'-TGCCGC-3\' consensus sequence and recognizes the methylated CpG within this element (By similarity). Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ZFP57

Research Areas

Epigenetics and Nuclear Signaling; Developmental biology; Stem cells