ZEB1 Antibody

Size

100ug

Clone Number

Aliases

AREB 6 antibody; AREB6 antibody; BZP antibody; Delta crystallin enhancer binding factor 1 antibody; DELTA EF1 antibody; FECD6 antibody; MGC133261 antibody; Negative regulator of IL 2 antibody; Negative regulator of IL2 antibody; NIL 2 A antibody; NIL 2 A zinc finger protein antibody; NIL 2A antibody; NIL-2-A zinc finger protein antibody; NIL2A antibody; Posterior polymorphous corneal dystrophy 3 antibody; PPCD3 antibody; Represses interleukin 2 expression antibody; TCF 8 antibody; TCF-8 antibody; TCF8 antibody; Transcription factor 8 (represses interleukin 2 expression) antibody; Transcription factor 8 antibody; ZEB 1 antibody; ZEB antibody; ZEB1 antibody; ZEB1_HUMAN antibody; ZFHEP antibody; ZFHX 1A antibody; ZFHX1A antibody; Zinc finger E box binding homeobox 1 antibody; Zinc finger E-box-binding homeobox 1 antibody; Zinc finger homeodomain enhancer binding protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P37275

Immunogen

Recombinant Human Zinc finger E-box-binding homeobox 1 protein (491-676AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5\\\'-CANNTG-3\\\'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

ZEB1

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Signal transduction