YTHDF2 Antibody

Size

100ug

Clone Number

Aliases

9430020E02Rik antibody; CAHL antibody; CLL associated antigen KW 14 antibody; CLL-associated antigen KW-14 antibody; HGRG8 antibody; High glucose regulated protein 8 antibody; High-glucose-regulated protein 8 antibody; NY REN 2 antibody; Renal carcinoma antigen NY REN 2 antibody; Renal carcinoma antigen NY-REN-2 antibody; YTH domain family 2 antibody; YTH domain family member 2 antibody; YTH domain family protein 2 antibody; YTH N6 methyladenosine RNA binding protein 2 antibody; YTHD2_HUMAN antibody; YTHDF 2 antibody; YTHDF2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y5A9

Immunogen

Recombinant Human YTH domain-containing family protein 2 protein (201-500AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability (PubMed:24284625, PubMed:26046440). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:22575960, PubMed:24284625, PubMed:25412658, PubMed:25412661). Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation (PubMed:24284625, PubMed:26046440).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

YTHDF2

Research Areas

Cell biology