• PIEZ1 rabbit pAb
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Upingbio

YP-Ab-18283-100UL

PIEZ1 rabbit pAb

PIEZ1 rabbit pAb

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  • Gene Name: PIEZO1 FAM38A KIAA0233
  • Immunogen: Synthesized peptide derived from human C-ternal PIEZ1
  • Specificity: This antibody detects endogenous levels of PIEZ1 at Human, Mouse,Rat
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 IHC 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Other Names: Piezo-type mechanosensitive ion channel component 1 (Membrane protein induced by beta-amyloid treatment) (Mib) (Protein FAM38A)
  • Function: Pore-forming subunit of a mechanosensitive non-specific cation channel . Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling . In the kidney, may contribute to the detection of intraluminal pressure changes and to urine flow sensing. Acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation . Plays a key role in blood vessel formation and vascular structure in both development and adult physiology (By similarity). Acts as sensor of phosphatidylserine (PS) flipping at the plasma membrane and governs morphogenesis of muscle cells. I
  • Species: Human;Mouse;Rat
  • Range: IHC;WB
  • Protein: Piezo-type mechanosensitive ion channel component 1 (Membrane protein induced by beta-amyloid treatment) (Mib) (Protein FAM38A)
  • DA: 277kD
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