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Upingbio
SKU:YP-Ab-18267-100UL
SEC13 rabbit pAb
SEC13 rabbit pAb
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- Gene Name: SEC13 D3S1231E SEC13L1 SEC13R
- Immunogen: Synthesized peptide derived from human SEC13
- Specificity: This antibody detects endogenous levels of SEC13 at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
- Function: Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles . Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum (By similarity). ; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex . It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 .
- Species: Human;Mouse;Rat
- Range: WB
- Protein: Protein SEC13 homolog (SEC13-like protein 1) (SEC13-related protein)
- DA: 35kD
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