• Arginase-1 (ABT-Arg1) mouse mAb
1 1

Upingbio

YP-Ab-18163-10UL

Arginase-1 (ABT-Arg1) mouse mAb

Arginase-1 (ABT-Arg1) mouse mAb

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Reaction species: Human
  • Gene Name: ARG1
  • Protein name: Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase)
  • Molecular weight (DA): 35kD
  • Immunogen: Synthesized peptide derived from human Arginase-1 AA range: 200-322
  • Specificity: The antibody can specifically recognize human Arginase-1 protein. In western blotting of HepG2 cell lysate, the antibody can label a 35 kDa band corresponding to Arginase-1.
  • Composition: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Source: Mouse, Monoclonal/IgG2b, kappa
  • Dilution ratio: IHC 1:200-1000. WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000
  • Purification process: Protein G
  • Concentration: mg/ml
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Background: Arginase-1 is a key enzyme in the urea cycle, which can catalyze the decomposition of arginine into ornithine and urea. Highly specific expression in liver tissue, but not in bile duct epithelial cells, hepatic sinusoidal endothelial cells, Kupffer cells and vascular endothelial cells.
  • Function: catalytic activity:L-arginine + H(2)O = L-ornithine + urea.,cofactor:Binds 2 manganese ions per subunit.,disease:Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.,induction:By arginine or homoarginine.,online information:Arginase entry,pathway:Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.,similarity:Belongs to the arginase family.,subunit:Homotrimer.,
View full details