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Upingbio
SKU:YP-Ab-18127-100UL
Nesprin 4 rabbit pAb
Nesprin 4 rabbit pAb
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- Gene Name: SYNE4 C19orf46
- Immunogen: Synthesized peptide derived from human Nesprin 4
- Specificity: This antibody detects endogenous levels of Nesprin 4 at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
- Function: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity). Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity).
- Species: Human;Mouse;Rat
- Range: WB
- Protein: Nesprin-4 (Nuclear envelope spectrin repeat protein 4)
- DA: 44kD
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