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Upingbio
SKU:YP-Ab-18121-100UL
ORAl1 rabbit pAb
ORAl1 rabbit pAb
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- Gene Name: ORAI1 CRACM1 TMEM142A
- Immunogen: Synthesized peptide derived from human ORAI1
- Specificity: This antibody detects endogenous levels of ORAI1 at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
- Function: Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 . CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT . Plays a prominent role in Ca(2+) influx at the basolateral membrane of mammary epithelial cells independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores. May mediate transepithelial transport of large quantities of Ca(2+) for milk secretion.
- Species: Human;Mouse;Rat
- Range: WB
- Protein: Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)
- DA: 33kD
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