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Upingbio

SKU:YP-Ab-18085-53UL

CD3(ABT295)mouse mAb

CD3(ABT295)mouse mAb

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Size
  • Reaction species: Human
  • Gene Name: CD3E T3E
  • Protein name: CD3, CD3E
  • Molecular weight (DA): 23kD
  • Immunogen: Synthesized peptide derived from human CD3, CD3E AA range: 1-100
  • Specificity: The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g. In western blotting of Jurkat cell lysate, the antibody can label a 23 kDa band corresponding to CD
  • Composition: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • Source: Mouse, Monoclonal/IgG2a, kappa
  • Dilution ratio: IHC 1:200-1000. WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000
  • Purification process: Protein G
  • Concentration: mg/ml
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Other Names: 4930549J05Rik;A430104F18Rik;AW552088;Cd247;CD247 antigen;CD247 antigen, zeta subunit;CD247 molecule;CD3;CD3 antigen, delta subunit;CD3 delta;CD3 epsilon;CD3 eta;CD3 gamma;CD3 molecule delta polypeptide;CD3 molecule, epsilon polypeptide;CD3 molecule, gamma polypeptide;CD3 zeta;CD3-DELTA;CD3d;CD3D antigen delta polypeptide;CD3d antigen, delta polypeptide (TiT3 complex);CD3d molecule delta;CD3d molecule delta CD3 TCR complex;CD3d molecule, delta (CD3-TCR complex);CD3D_HUMAN;CD3E;CD3e antigen;CD3E antigen epsilon polypeptide;CD3e antigen, epsilon polypeptide (TiT3 complex);CD3e molecule epsilon;CD3e molecule epsilon CD3 TCR complex;CD3e molecule, epsilon (CD3-TCR complex);CD3epsilon;CD3G;CD3g antigen;CD3G antigen gamma polypeptide;CD3g antigen, gamma polypeptide (TiT3 complex);CD3g molecule gamma;CD3g molecule gamma CD3 TCR complex;CD3g molecule, gamma (CD3-TCR complex);CD3H;CD3Q;CD3Z;CD3zeta;Ctg3;FLJ17620;FLJ17664;FLJ18683;FLJ79544;FLJ94613;IMD19;Leu-4;MGC138597;OKT3, delta chain;OTTHUMP0
  • Background: CD3 protein contains ε、γ、δ and ζ four subunits, including extracellular, transmembrane and intracellular domains. CD3 is a T cell marker, which is not expressed by B cells. CD3 complex mediates TCR antigen recognition, leading to T cell proliferation and cytokine release. It is mainly used for the diagnosis of T-cell lymphoma, with high specificity but low sensitivity. In order to improve the accuracy of diagnosis, it is usually combined with CD45RO in clinical application.
  • Function: function:The CD3 complex mediates signal transduction.,online information:CD3E mutation db,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 1 ITAM domain.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.,
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