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Upingbio
SKU:YP-Ab-18068-100UL
SELK rabbit pAb
SELK rabbit pAb
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- Gene Name: SELK HSPC030 HSPC297
- Immunogen: Synthesized peptide derived from human SELK
- Specificity: This antibody detects endogenous levels of SELK at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
- Function: Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins . Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function . Plays a role in protection of cells from ER stress-induced apoptosis . Protects cells from oxidative stress when overexpressed in cardiomyocytes .
- Species: Human;Mouse;Rat
- Range: WB
- Protein: Selenoprotein K (SelK)
- DA: 10kD
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