• CBP20 Rabbit pAb
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Upingbio

YP-Ab-17917-100UL

CBP20 Rabbit pAb

CBP20 Rabbit pAb

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  • Gene Name: NCBP2
  • Immunogen: Synthetic peptide corresponding to amino acids N-terminus of Human CBP20.
  • Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/200 IF: 1/50-1/200 IP: 1/50-1/100
  • Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
  • Other Names: Nuclear cap-binding protein subunit 2; 20 kDa nuclear cap-binding protein; Cell proliferation-inducing gene 55protein; NCBP 20 kDa subunit; CBP20; NCBP-interacting protein 1; NIP1; NCBP2; CBP20; ORF Names: PlG55
  • Background: In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC). CBC consists of two cap binding proteins, CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80.
  • Species: Human,Mouse,Rat
  • Range: WB, IHC-P, ICC/IF,IP
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