• CENPE rabbit pAb
1 1

Upingbio

YP-Ab-17900-100UL

CENPE rabbit pAb

CENPE rabbit pAb

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: CENPE
  • Immunogen: Synthesized peptide derived from human CENPE
  • Specificity: This antibody detects endogenous levels of CENPE at Human, Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Function: Microtubule plus-end-directed kinetochore motor which plays an important role in chromosome congression, microtubule-kinetochore conjugation and spindle assembly checkpoint activation. Drives chromosome congression (alignment of chromosomes at the spindle equator resulting in the formation of the metaphase plate) by mediating the lateral sliding of polar chromosomes along spindle microtubules towards the spindle equator and by aiding the establishment and maintenance of connections between kinetochores and spindle microtubules . The transport of pole-proximal chromosomes towards the spindle equator is favored by microtubule tracks that are detyrosinated . Acts as a processive bi-directional tracker of dynamic microtubule tips; after chromosomes have congressed, continues to play an active role at kinetochores, enhancing their links with dynamic microtubule ends . Suppresses chromosome c
  • Species: Human;Mouse
  • Range: WB
  • Protein: Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-related protein CENPE)
  • DA: 297kD
View full details