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Upingbio
SKU:YP-Ab-17894-10UL
TBK1 Rabbit mAb
TBK1 Rabbit mAb
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- Reaction species: Human,Mouse,Rat
- Gene Name: TBK1
- Molecular weight (DA): Calculated MW: 84 kDa; Observed MW: 84 kDa
- Immunogen: synthesized peptide derived from human NAK/TBK1 (N-term)
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Other Names: TBK1; NAK; Serine/threonine-protein kinase TBK1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1
- Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.
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