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Upingbio
SKU:YP-Ab-17884-53UL
Phospho-AMPK alpha 2 (Thr172) Rabbit mAb
Phospho-AMPK alpha 2 (Thr172) Rabbit mAb
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- Reaction species: Human;Mouse;Rat
- Gene Name: PRKAA2
- Molecular weight (DA): Calculated MW: 62 kDa
- Immunogen: synthesized peptide derived from human AMPK alpha
- Dilution ratio: WB: 1/500-1/1000
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Other Names: PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase
- Background: AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia.
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