• Phospho-TrkB (Tyr817) Rabbit mAb
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Upingbio

YP-Ab-17882-100UL

Phospho-TrkB (Tyr817) Rabbit mAb

Phospho-TrkB (Tyr817) Rabbit mAb

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Size
  • Reaction species: Human,Mouse,Rat
  • Gene Name: NTRK2
  • Molecular weight (DA): Calculated MW: 92 kDa; Observed MW: 140 kDa
  • Immunogen: synthesized peptide derived from human Phospho-TrkB (Y817)
  • Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/30
  • Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Other Names: NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B
  • Background: The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.
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