• Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit mAb
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Upingbio

YP-Ab-17881-53UL

Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit mAb

Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit mAb

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Size
  • Reaction species: Human
  • Gene Name: MAPK1/MAPK3
  • Molecular weight (DA): Calculated MW: 42,44 kDa; Observed MW: 42,44 kDa
  • Immunogen: synthesized peptide derived from human Phospho-Erk1 (T202/Y204) + Erk2 (T185/Y187)
  • Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
  • Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Other Names: MAPK1/MAPK3
  • Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
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