• Phospho-AKT (Ser473) Rabbit mAb
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Upingbio

YP-Ab-17876-100UL

Phospho-AKT (Ser473) Rabbit mAb

Phospho-AKT (Ser473) Rabbit mAb

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  • Reaction species: Human,Mouse,Rat
  • Gene Name: AKT1
  • Immunogen: synthetic phosphopeptide corresponding to residues surrounding Ser473 of human AKT1
  • Dilution ratio: WB: 1/500-1/1000
  • Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Other Names: AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
  • Background: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
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