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Upingbio
SKU:YP-Ab-17871-100UL
RNase 1 Rabbit pAb
RNase 1 Rabbit pAb
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- Gene Name: RNASE1
- Immunogen: Fusion protein of human RNASE1
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Other Names: RAC1; RIB1; RNS1
- Background: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
- Species: Human,Mouse,Rat
- Range: WB,IHC-P
- DA: Calculated MW: 18 kDa; Observed MW: 18 kDa
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