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Upingbio
SKU:YP-Ab-17866-53UL
Histone H2A.X Rabbit mAb
Histone H2A.X Rabbit mAb
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- Reaction species: Human,Mouse,Rat
- Gene Name: H2AX
- Molecular weight (DA): Calculated MW: 15 kDa; Observed MW: 15 kDa
- Immunogen: synthetic peptide of human Histone H2A.X
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Other Names: H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X
- Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
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