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Upingbio
SKU:YP-Ab-17843-100UL
Histone H3 Rabbit mAb
Histone H3 Rabbit mAb
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- Reaction species: Human,Mouse,Rat
- Gene Name: H3C1
- Molecular weight (DA): Calculated MW: 15 kDa; Observed MW:15 kDa
- Immunogen: Peptide
- Dilution ratio: WB：1/1000-1/5000，IHC-P：1/50-1/100
- Storage: Store at -20°C. Avoid freeze/thaw cycles.
- Other Names: Histone H3.1
- Background: Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. Histone H3 is primarily acetylated at Lys9, 14, 18, 23, 27, and 56. Acetylation of H3 at Lys9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10, Ser28, and Thr11 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
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