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Upingbio
SKU:YP-Ab-17839-100UL
Thioredoxin Reductase 1 Rabbit pAb
Thioredoxin Reductase 1 Rabbit pAb
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- Gene Name: TXNRD1
- Immunogen: A synthesized peptide derived from human TXNRD1
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles
- Other Names: TR; TR1; TXNR; TRXR1; GRIM-12
- Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
- Species: Human,Mouse,Rat
- Range: WB,IHC-P,ICC/IF,IP,FC
- DA: Calculated MW: 71 kDa; Observed MW: 55 kDa
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