• Phospho-IKB alpha (Ser36) Rabbit mAb
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Upingbio

YP-Ab-17827-53UL

Phospho-IKB alpha (Ser36) Rabbit mAb

Phospho-IKB alpha (Ser36) Rabbit mAb

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Size
  • Reaction species: Human,Mouse
  • Gene Name: NFKBIA
  • Molecular weight (DA): Calculated MW: 36 kDa;Observed MW:39kDa Clonality
  • Immunogen: synthesized peptide derived from human Phospho-IKB alpha (S36)
  • Dilution ratio: WB: 1/500-1/1000 FC: 1/50
  • Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Other Names: I kappa B alpha; IkappaBalpha; IkB-alpha; IKBA; IKBalpha; MAD3; NF kappa B inhibitor alpha; NFKBI; NFKBIA;
  • Background: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
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