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Upingbio
SKU:YP-Ab-17790-100UL
CD86 Rabbit pAb
CD86 Rabbit pAb
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- Gene Name: CD86
- Immunogen: Recombinant protein of human CD86 (NP_787058.4).
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Other Names: CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86
- Background: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
- Species: Human,Mouse,Rat
- Range: WB,IHC-P,ICC/IF
- DA: Calculated MW: 38 kDa; Observed MW: 74 kDa
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