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Upingbio
SKU:YP-Ab-17785-100UL
CD163 Mouse mAb
CD163 Mouse mAb
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- Reaction species: Human,Mouse
- Gene Name: CD163
- Molecular weight (DA): Calculated MW: 125 kDa
- Immunogen: Purified recombinant fragment of human CD163 expressed in E. Coli.
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/100-1/200 ELISA: 1/10000
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Other Names: M130; MM130; SCARI1
- Background: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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