• PPAR alpha Mouse mAb
1 1

Upingbio

YP-Ab-17763-53UL

PPAR alpha Mouse mAb

PPAR alpha Mouse mAb

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Size
  • Reaction species: Human,Monkey
  • Gene Name: PPARA
  • Molecular weight (DA): Calculated MW: 52 kDa
  • Immunogen: Purified recombinant fragment of human PPARA expressed in E. Coli.
  • Dilution ratio: WB: 1/500-1/1000 FC: 1/50-1/100 ELISA: 1/10000
  • Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Other Names: PPAR; NR1C1; hPPAR; PPARalpha
  • Background: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
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