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Upingbio

SKU:YP-Ab-17758-100UL

Rat Anti-Mouse/Human CD11b mAb (PE/TR)

Rat Anti-Mouse/Human CD11b mAb (PE/TR)

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  • Reaction species: Human,Mouse
  • Gene Name: Mouse/Human CD11b
  • Immunogen: synthesized peptide derived from Human CD11b
  • Dilution ratio: FC: 5μL per test for million cells or whole blood in 100 μL volume.
  • Storage: Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.
  • Other Names: Integrin alpha-M; Itgam; CD11 antigen-like family member B; CR-3 alpha chain; Leukocyte adhesion receptor MO1; CD11b
  • Background: CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
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