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Upingbio
SKU:YP-Ab-17757-10UL
Rat Anti-Mouse CD86 mAb (PE/TR)
Rat Anti-Mouse CD86 mAb (PE/TR)
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- Reaction species: Human,Mouse
- Gene Name: Mouse CD86
- Immunogen: synthesized peptide derived from Mouse CD86
- Dilution ratio: FC: 5μL per test for million cells or whole blood in 100 μL volume.
- Storage: Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.
- Other Names: T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1
- Background: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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