• MYLK Rabbit pAb
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Upingbio

YP-Ab-17743-100UL

MYLK Rabbit pAb

MYLK Rabbit pAb

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  • Gene Name: MYLK
  • Immunogen: A synthesized peptide derived from human Myosin light chain kinase
  • Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
  • Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Other Names: KMLS; KRP; MLCK; MYLK; myosin light chain kinase; smooth muscle and non-muscle isozymes; myosin light polypeptide kinase; telokin
  • Background: Regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessary for physiological and asthmatic airway resistance.
  • Species: Human,Mouse,Rat
  • Range: WB,IHC-P,ICC/IF,FC
  • DA: Calculated MW: 211 kDa; Observed MW: 130-140 kDa
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