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Upingbio
SKU:YP-Ab-17730-53UL
AKT1 Rabbit mAb
AKT1 Rabbit mAb
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- Reaction species: Human,Mouse,Rat
- Gene Name: AKT1
- Molecular weight (DA): Calculated MW: 56 kDa
- Immunogen: synthesized peptide derived from human AKT1
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Background: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
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