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Upingbio
SKU:YP-Ab-17729-10UL
PD-L1 Rabbit mAb
PD-L1 Rabbit mAb
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- Reaction species: Human,Mouse,Rat
- Gene Name: CD274
- Molecular weight (DA): Calculated MW:33kDa;Observed MW:46kDa
- Immunogen: synthesized peptide derived from human PD-L1 (CD274)
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/100-1/200
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Other Names: B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274;
- Background: Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens.
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