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Upingbio
SKU:YP-Ab-17719-100UL
Caspase 14 Rabbit mAb
Caspase 14 Rabbit mAb
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- Reaction species: Human,Mouse,Rat
- Gene Name: CASP14
- Molecular weight (DA): Calculated MW: 28 kDa; Observed MW: 28 kDa
- Immunogen: synthesized peptide derived from human Caspase-14
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Other Names: CASP14; Caspase-14; Caspase 14; MICE; CASP-14
- Background: Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. May also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
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