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Upingbio

SKU:YP-Ab-17710-100UL

ZIP8 rabbit pAb

ZIP8 rabbit pAb

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  • Gene Name: SLC39A8 BIGM103 ZIP8 PP3105
  • Immunogen: Synthesized peptide derived from human ZIP8
  • Specificity: This antibody detects endogenous levels of ZIP8 at Human, Mouse,Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
  • Function: Electroneutral transporter of the plasma membrane mediating the cellular uptake of zinc and manganese, two divalent metal cations important for development, tissue homeostasis or immunity . Functions as an energy-dependent symporter, transporting through the membranes an electroneutral complex composed of a divalent metal cation, a bicarbonate and a selenite anion or yet a metal cation and two bicarbonate anions . May also transport iron, mercury and cobalt through membranes . Beside these endogenous cellular substrates, also imports cadmium a non-essential metal which is cytotoxic and carcinogenic . Through zinc import, indirectly regulates the metal-dependent transcription factor MTF1 and the expression of some metalloproteases involved in cartilage catabolism and also probably heart development . Also indirectly regulates the expression of proteins involved in cell morphology and cyt
  • Species: Human;Mouse;Rat
  • Range: WB
  • Protein: Zinc transporter ZIP8 (BCG-induced integral membrane protein in monocyte clone 103 protein) (LIV-1 subfamily of ZIP zinc transporter 6) (LZT-Hs6) (Solute carrier family 39 member 8) (Zrt- and Irt-like
  • DA: 51kD
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