• YTDC1 rabbit pAb
1 1

Upingbio

YP-Ab-17271-100UL

YTDC1 rabbit pAb

YTDC1 rabbit pAb

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: YTHDC1 KIAA1966 YT521
  • Immunogen: Synthesized peptide derived from human N-ternal YTDC1
  • Specificity: This antibody detects endogenous levels of YTDC1 at Human,Rat
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Rabbit,polyclonal
  • Dilution ratio: WB 1:500-2000 IHC 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: YTH domain-containing protein 1 (Putative splicing factor YT521)
  • Function: Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs . M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability . Acts as a key regulator of exon-inclusion or exon-skipping during alternative splicing via interaction with mRNA splicing factors SRSF3 and SRSF10 . Specifically binds m6A-containing mRNAs and promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing . In contrast, interaction with SRSF3 prevents interaction with SRSF10, a splicing factor that promotes exon skipping: this prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing . May also regulate
  • Species: Human,Rat
  • Range: IHC,WB
  • Protein: YTH domain-containing protein 1 (Putative splicing factor YT521)
View full details