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Upingbio
SKU:YP-Ab-17250-100UL
STIM1 rabbit pAb
STIM1 rabbit pAb
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- Gene Name: STIM1 GOK
- Immunogen: Synthesized peptide derived from human N-ternal STIM1
- Specificity: This antibody detects endogenous levels of STIM1 at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Rabbit,polyclonal
- Dilution ratio: WB 1:500-2000 IHC 1:50-200
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Stromal interaction molecule 1
- Function: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores . Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 . Involved in enamel formation . Activated following interaction with STIMATE, leading to promote STIM1 conformational switch .
- Species: Human, Mouse,Rat
- Range: IHC,WB
- Protein: Stromal interaction molecule 1
- DA: 75kD
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