• ACE2 Mouse mAb(2C1)
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Upingbio

YP-Ab-17213-53UL

ACE2 Mouse mAb(2C1)

ACE2 Mouse mAb(2C1)

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  • Reaction species: Human, Mouse,Rat
  • Gene Name: ACE2 UNQ868/PRO1885
  • Protein name: ACE2
  • Molecular weight (DA): 120-135kD
  • Immunogen: Synthesized peptide derived from human ACE2
  • Specificity: This antibody detects endogenous levels of ACE2 at Human, Mouse,Rat
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Mouse,monoclonal
  • Dilution ratio: WB 1:500-2000 IHC 1:50-200. IF 1:50-200
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
  • Concentration: mg/ml
  • Storage: -20°C/1 year
  • Other Names: Angiotensin-converting enzyme 2 (EC 3.4.17.23) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]
  • Function: cofactor:Binds 1 chloride ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Activated by chloride and fluoride, but not bromide. Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat.,function:Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.,induction:Up-regulated in failing heart.,PTM:N-glycosylation on Asn-90 may limit SARS infectivity.,similarity:Belongs to the peptidase M2 family.,subunit:Interacts with ITGB1. Interacts with SARS-CoV and HCoV-NL63
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