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SKU:YP-Ab-17209-53UL
14-3-3 eta Mouse mAb(5B2)
14-3-3 eta Mouse mAb(5B2)
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- Reaction species: Human, Mouse,Rat
- Gene Name: YWHAH YWHA1
- Protein name: 14-3-3 eta
- Molecular weight (DA): 28kD
- Immunogen: Synthesized peptide derived from human 14-3-3 eta
- Specificity: This antibody detects endogenous levels of 14-3-3 eta at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Mouse,monoclonal
- Dilution ratio: WB 1:500-2000 IHC 1:50-200
- Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- Concentration: mg/ml
- Storage: -20°C/1 year
- Other Names: 14-3-3 protein eta (Protein AS1)
- Function: function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.,similarity:Belongs to the 14-3-3 family.,subunit:Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with RGNEF and PCTK1 (By similarity). Weakly interacts with CDKN1B.,tissue specificity:Expressed mainly in the brain and present in other tissues albeit at lower levels.,
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