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Upingbio

SKU:YP-Ab-17151-53UL

HMGB1 (PTR2339) Mouse mAb

HMGB1 (PTR2339) Mouse mAb

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  • Reaction species: Human, Mouse,Rat
  • Gene Name: HMGB1 HMG1
  • Protein name: High mobility group protein B1 (High mobility group protein 1) (HMG-1)
  • Molecular weight (DA): 24kDa
  • Immunogen: Synthesized peptide derived from human HMGB1
  • Specificity: This antibody detects endogenous levels of HMGB1 at Human, Mouse,Rat
  • Composition: PBS, pH7.4, 50% glycerol, 0.03%Proclin 300
  • Source: Mouse,monoclonal:IgG1, Kappa
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: Protein G
  • Storage: -20°C/1 year
  • Other Names: High mobility group protein B1 (High mobility group protein 1) (HMG-1)
  • Background: high mobility group box 1(HMGB1) Homo sapiens This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015],
  • Function: function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
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