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SKU:YP-Ab-17145-100UL
Beclin-1 (Phospho Ser93/96) Rabbit pAb
Beclin-1 (Phospho Ser93/96) Rabbit pAb
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- Gene Name: BECN1 GT197
- Immunogen: Synthesized peptide derived from human Beclin-1 (Phospho Ser93/96)
- Specificity: This antibody detects endogenous levels of Beclin-1 (Phospho Ser93/96) Rabbit pAb at Human, Mouse,Rat
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Rabbit,polyclonal
- Dilution ratio: WB 1:500-2000 IHC 1:50-200
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)
- Background: beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
- Function: function:Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.,similarity:Belongs to the beclin family.,subcellular location:Expressed in dendrites and cell bodies of cerebellar Purkinje cells.,subunit:Interacts with GOPC and GRID2. Interacts with AMBRA1. Probably forms a complex with AMBRA1 and PIK3C3 (By similarity). Interacts with BCL2 and BCL2L1.,tissue specificity:Ubiquitous.,
- Species: Human, Mouse,Rat
- Range: IHC,WB
- Protein: Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)
- DA: 55kD
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