• TROP-2 Polyclonal Antibody
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Upingbio

YP-Ab-17073-100UL

TROP-2 Polyclonal Antibody

TROP-2 Polyclonal Antibody

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  • Gene Name: TACSTD2
  • Immunogen: The antiserum was produced against synthesized peptide derived from human TACD2. AA range:131-180
  • Specificity: TROP-2 Polyclonal Antibody detects endogenous levels of TROP-2 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: TACSTD2; GA733-1; M1S1; TROP2; Tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1
  • Background: This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009],
  • Function: disease:Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.,function:GA733 tumor-associated antigen gene family may function as growth factor receptors.,PTM:The N-terminus is blocked.,similarity:Contains 1 thyroglobulin type-1 domain.,tissue specificity:Placenta, pancreatic carcinoma cell lines.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Tumor-associated calcium signal transducer 2
  • DA: 35kD
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