• Connexin 46 Polyclonal Antibody
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Upingbio

YP-Ab-17005-100UL

Connexin 46 Polyclonal Antibody

Connexin 46 Polyclonal Antibody

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  • Gene Name: GJA3
  • Immunogen: The antiserum was produced against synthesized peptide derived from human GJA3. AA range:151-200
  • Specificity: Connexin 46 Polyclonal Antibody detects endogenous levels of Connexin 46 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:100-500;IF/ICC 1:100-500;ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: GJA3; Gap junction alpha-3 protein; Connexin-46; Cx46
  • Background: The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3). [provided by RefSeq, Jan 2010],
  • Function: disease:Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3) [MIM:601885]. CZP3 is a form of autosomal dominant congenital cataract.,function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and non-junctional ("hemi-") channels.,
  • Species: Human;Mouse;Rat
  • Range: IHC;IF;ELISA
  • Protein: Gap junction alpha-3 protein
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