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Upingbio

SKU:YP-Ab-16976-100UL

COL19A1 Polyclonal Antibody

COL19A1 Polyclonal Antibody

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  • Gene Name: COL19A1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human Collagen XIX alpha1. AA range:421-470
  • Specificity: COL19A1 Polyclonal Antibody detects endogenous levels of COL19A1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: COL19A1; Collagen alpha-1(XIX) chain; Collagen alpha-1(Y) chain
  • Background: This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced. [provided by RefSeq, Jul 2008],
  • Function: domain:The numerous interruptions in the triple helix may make this molecule either elastic or flexible.,function:May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,subunit:Oligomer; disulfide-linked.,tissue specificity:Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Collagen alpha-1(XIX) chain
  • DA: 120kD
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