• Claudin-2 Polyclonal Antibody
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Upingbio

YP-Ab-16956-100UL

Claudin-2 Polyclonal Antibody

Claudin-2 Polyclonal Antibody

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  • Gene Name: CLDN2
  • Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 2. AA range:181-230
  • Specificity: Claudin-2 Polyclonal Antibody detects endogenous levels of Claudin-2 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CLDN2; PSEC0059; SP82; Claudin-2; SP82
  • Background: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010],
  • Function: function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
  • Species: Human;Mouse
  • Range: WB;IHC;IF;ELISA
  • Protein: Claudin-2
  • DA: 25kD
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