• Claudin-10 Polyclonal Antibody
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Upingbio

YP-Ab-16953-100UL

Claudin-10 Polyclonal Antibody

Claudin-10 Polyclonal Antibody

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  • Gene Name: CLDN10
  • Immunogen: The antiserum was produced against synthesized peptide derived from human Claudin 10. AA range:179-228
  • Specificity: Claudin-10 Polyclonal Antibody detects endogenous levels of Claudin-10 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CLDN10; Claudin-10; OSP-like protein
  • Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010],
  • Function: function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,
  • Species: Human; Mouse; Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Claudin-10
  • DA: 25kD
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