• Talin (phospho-Ser425) rabbit pAb
1 1

Upingbio

YP-Ab-16919-100UL

Talin (phospho-Ser425) rabbit pAb

Talin (phospho-Ser425) rabbit pAb

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: TLN1 KIAA1027 TLN
  • Immunogen: Synthesized phosho peptide around human Talin (Ser425)
  • Specificity: This antibody detects endogenous levels of Human Mouse Rat Talin (phospho-Ser425)
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Talin-1
  • Background: This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009],
  • Function: function:Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.,similarity:Contains 1 FERM domain.,similarity:Contains 1 I/LWEQ domain.,subcellular location:Colocalizes with LAYN at the membrane ruffles.,subunit:Binds with high affinity to vinculin and with low affinity to integrins. Interacts with PIP5K1C and NRAP. Interacts with LAYN. Interacts with SYNM.,
  • Species: Human;Mouse;Rat
  • Range: WB
  • Protein: Talin (Ser425)
  • DA: 269kD
View full details